Tetracycline in Sumycin is used for acne. The drug is effective in bronchitis, urinary tract infections and syphilis. It has a broad spectrum of action against Gram-positive and Gram-negative bacteria. Recommended for adolescents and adults, the dosage depends on the diagnosis. It is used for long-term therapy.
no RX
Dosage | Package | Per Item | Per Pack | Order |
250 mg |
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500 mg |
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The drug is known under the trade name Sumycin. This name is registered in pharmaceutical registries and is used to identify the drug in pharmacies, medical institutions and among health care professionals. Sumycin is recognized for its effectiveness in the therapy of various bacterial infections requiring reliable antibacterial action. The name was chosen by the manufacturers to indicate its belonging to a specific group of antibiotics, emphasizing its importance and versatility in clinical practice.
The international nonproprietary name of this medicine is tetracycline. This term is adopted by the international community to designate the active substance that provides the therapeutic effect. Tetracycline belongs to the class of tetracycline antibiotics, known for their ability to inhibit the growth of a wide range of bacteria. The name is standardized by the World Health Organization, which ensures uniformity in the prescription and production of this drug in different countries.
The drug is available in several forms, which makes it convenient for use depending on the age of the patient and the peculiarities of treatment. The main options include:
Each form is designed to meet the needs of therapy: tablets and capsules are suitable for adults, while the suspension is convenient for children or patients with difficulty swallowing solid forms. The choice of form is determined by the physician based on the diagnosis and condition of the patient.
The main active ingredient is tetracycline, an antibiotic from the group of tetracyclines. Auxiliary components depend on the form of release. In tablets, the following are used:
The capsules add gelatin for the shell and povidone as a solvent. The suspension contains sucrose to improve taste, flavorings (e.g., orange) and xanthan gum as a thickener. The composition is balanced to ensure stability and bioavailability.
Sumycin has bacteriostatic action, inhibiting protein synthesis in bacterial cells. It binds to 30S-subunit of ribosomes, preventing the process of translation and formation of peptide chains, which stops the growth and multiplication of microorganisms. The drug is effective against Gram-positive bacteria (Staphylococcus aureus, Streptococcus pneumoniae), Gram-negative pathogens (Escherichia coli, Haemophilus influenzae) and atypical pathogens (Chlamydia spp., Mycoplasma pneumoniae, Rickettsia spp.).
The mechanism of action makes the drug useful in infections requiring a broad spectrum of antibacterial action. Sumycin is particularly valuable when therapy against intracellular pathogens or bacteria resistant to other antibiotics is needed.
After oral administration, the active substance is absorbed in the gastrointestinal tract, predominantly in the small intestine, reaching maximum plasma concentrations after 2-4 hours. Bioavailability is about 60-80%, but decreases when taken with food, especially rich in calcium or iron, due to the formation of chelate complexes. For optimal absorption it is recommended to take the drug on an empty stomach.
The component is well distributed in the body, penetrating into the lungs, liver, kidneys, bones, skin and soft tissues. Binding to plasma proteins is about 20-65%, which provides sufficient distribution to the foci of infection. Concentrations in tissues often exceed plasma concentrations, which enhances the effect in systemic infections.
Metabolism is minimal: more than 90% of the dose taken remains unchanged. A minor part undergoes metabolic transformations in the liver to form inactive derivatives.
Extracted mainly through the kidneys (60-70% unchanged) by tubular filtration, as well as with bile and feces (20-30%). The elimination half-life is 6-11 hours, but increases in case of renal dysfunction.
Sumycin is prescribed for the treatment of infections caused by sensitive microorganisms:
The drug is also used for chronic inflammatory processes such as moderate to severe acne. Prescribing requires confirmation of the sensitivity of the pathogen.
The use of Sumycin is prohibited in:
Prescribe with caution in cases of peptic ulcer and photosensitivity.
Tablets and capsules are taken orally, drinking plenty of water (200-250 ml), 1 hour before a meal or 2 hours after to avoid interaction with food. The suspension is prepared by adding water up to the mark, shake before use. Patients are advised to avoid lying down after administration to prevent esophageal irritation.
Dosage depends on the infection:
In renal insufficiency:
In hepatic insufficiency the dose is reduced to 250 mg/day.
Unwanted reactions include:
Treatment should be discontinued if symptoms are severe.
Exceeding the dose of Sumycin causes nausea, vomiting, diarrhea, convulsions.
In overdose:
The medication affects:
Alcohol reduces efficacy and increases toxicity and is avoided. Dairy products slow absorption.
Sumycin is contraindicated in pregnancy (category D) and lactation due to the risk to the fetus and child.
Dizziness may make driving difficult.
The elderly require monitoring of renal function. Do not use in children under 8 years of age due to dental risk.